Company Profile

Vertex Pharmaceuticals

Company Overview

At Vertex, we bring together the brightest minds in the relentless pursuit of creating transformative medicines for people with serious and life-threatening diseases. Founded in 1989 in Cambridge, Massachusetts, we are one of only a handful of biotechnology companies founded since 1976 that has discovered and developed four or more approved medicines in our own labs. In addition to the four medicines we’ve developed to treat the underlying cause of cystic fibrosis, we have ongoing research programs focused on the underlying mechanisms of other serious diseases.

Our U.S. headquarters are in Boston’s Innovation District, our International headquarters are located in London, UK, and we have research and development (R&D) sites and commercial offices in the U.S., Europe, Canada, Australia and Latin America. With more than two-thirds of our employees dedicated to research and development (R&D), we are consistently recognized as one of the industry’s top places to work, including nine consecutive years on Science magazine’s Top Employers list. For company updates and to learn more about us visit www.vrtx.com. You can also get to know us on Facebook, Twitter and YouTube.

Positions Available
  • < a day ago

    Principal Engineer, Microsoft 365 Security & Data Protection

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:This person will be responsible for the day-to-day administration of the Microsoft 365 Purview and Entra ID platforms, as well as the Veritas Data Insight platform, in a heavily-regulated GxP environment. This person will be responsible for working with business and technical leaders to identify systems containing critical data and labeling them accordingly. S/he will be responsible for creating data protection awareness programs for end-users and using standardized ...

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  • 6 days ago

    Principal Engineer, AutoQC and Data Consumption Solutions

    Vertex Pharmaceuticals - San Diego, California, United States

    Job DescriptionVertex is a global biotechnology company that invests in scientific innovation. The Data, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group's mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront ...

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  • 14 days ago

    Principal Engineer, Cloud Infrastructure

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionPrincipal Cloud Infrastructure EngineerLocation:Boston, MA (Vertex Headquarters) Position SummaryThe Principal Cloud Infrastructure Engineer will lead the design, implementation, and optimization of enterprise-scale Azure cloud infrastructure with a strong emphasis on automation, operational excellence, and emerging AI technologies. This role will serve as a technical leader responsible for architecting resilient, scalable, and secure cloud solutions that support critical business ...

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  • 14 days ago

    Vertex Summer 2026 Intern, External Manufacturing - Automation Engineering Business Analyst

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionKickstart Your Career at Vertex!Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, ...

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  • 15 days ago

    Director of Financial Planning and Analysis, Supply Chain and Manufacturing Operations

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionThe Director of Financial Planning and Analysis, Supply Chain and Manufacturing Operations (BSMO) is a key member of Vertex's Financial Planning & Analysis team. This role will partner closely with Commercial Manufacturing and Tech Ops (CMTO), Commercial Finance and Disease Strategy Team (DST) Finance in support of our Cell and Gene Therapies portfolio, with a specific focus on CASGEVY, the first-ever approved CRISPR-based gene-editing therapy used to treat Sickle Cell Disease ...

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  • 17 days ago

    Human Resources Business Partner Senior Director, Biopharmaceutical Sciences & Manufacturing Operations

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionWe are seeking a strategic, influential, and business-savvyHR Business Partner Senior Directorto support the Biopharmaceutical Sciences & Manufacturing Operations (BSMO) team at Vertex during a pivotal phase of growth and innovation. In this role, you will act as the key HR leader and strategic advisor to senior executives across one or more major BSMO sub-functions. Reporting to the Executive Director, HRBP Lead for BSMO, you will help shape organizational strategy, culture, ...

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  • 17 days ago

    Director, Engineering Operations (Cell and Genetic Therapies)

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionDirector, Engineering Operations (Cell and Genetic Therapies)General Summary:The Director, Engineering Operations - CGT is responsible for building and leading the Engineering Operations team within the broader Biopharmaceutical Sciences - Cell & Gene Therapy (CGT) Manufacturing and Process Engineering organization. Vertex is rapidly progressing a pipeline of exciting cell and genetic therapy and biologics programs requiring development of sustainable and scalable clinical and ...

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  • 24 days ago

    Principal Cloud Security Services Engineer, Application Security

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:The Cybersecurity Senior Engineer II provides day-to-day technical support for one or more security capabilities and services, including the implementation of new solutions and processes to increase efficiencies, and optimize and expand service offerings for both on premise and the cloud. Key Duties and Responsibilities:Collaborates with members of the technical and business communities to integrate new applications into the Vertex ecosystem Analyzes and resolves ...

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  • 29 days ago

    Senior Director, CMC and Manufacturing Data & Technology

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group's mission is to improve the lives of patients through data, and technology innovation - with AI at the core of our transformation strategy. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission ...

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  • 29 days ago

    R&D Quality Governance & Risk Management Director

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral position summary: The Director of R&D Quality Governance & Risk Management will serve as a strategic leader and trusted partner within R&D Quality, responsible for shaping, implementing, and continuously improving the governance framework that supports risk-based decision-making across Vertex's R&D portfolio. This role will integrate governance excellence, enterprise risk management, and clinical quality management system expertise to drive a unified "One State of Quality" ...

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